Dr. Konstantin Tziridis | Hearing Loss and Tinnitus | Best Researcher Award

Research Assistant at University Hospital Erlangen, Germany

Dr. rer. nat. Konstantin Tziridis is an accomplished neuroscientist specializing in auditory research, particularly the mechanisms and treatment strategies for tinnitus. His extensive work in translational research has contributed to significant advancements in understanding auditory phantom perception. As a research assistant at the University Hospital Erlangen’s ENT Clinic, he has been involved in experimental otolaryngology, focusing on bridging the gap between basic neuroscience and clinical applications. His contributions to neurophysiology and auditory sciences have earned him recognition in the field, making his research pivotal to the scientific community.

Profile

ORCID

Education

Dr. Tziridis pursued his doctoral studies at the Hertie Institute for Clinical Brain Research in Tübingen from 2001 to 2008. His PhD research laid the foundation for his career in auditory neuroscience, providing him with a deep understanding of brain mechanisms associated with hearing and perception. Over the years, he has continued to expand his expertise through academic engagements and experimental research, integrating neurobiological principles into translational applications to improve hearing-related conditions.

Experience

Since 2008, Dr. Tziridis has been working as a research assistant at the University Hospital Erlangen’s ENT Clinic, where he specializes in experimental otolaryngology. His career has been marked by significant contributions to basic neurobiological research, including auditory perception and tinnitus mechanisms. In 2019, he expanded his research scope to translational studies aimed at alleviating phantom auditory perceptions in tinnitus patients. His experience also includes teaching neurophysiology courses for molecular, dental, and human medicine specialists since 2016, solidifying his role as an educator in the field. Additionally, his engagement in mentoring doctoral students and supervising graduate-level theses has contributed to the scientific development of early-career researchers.

Research Interests

Dr. Tziridis is primarily interested in auditory neuroscience, with a special focus on tinnitus development and treatment. His research explores the structural and neurobiological changes within the auditory system, including synaptopathy, extracellular matrix alterations, and the impact of stochastic resonance on auditory perception. Through experimental studies on Mongolian gerbils, he has investigated auditory processing mechanisms, contributing to innovative approaches in hearing research. His interdisciplinary work integrates neurophysiology, neuromodulation, and predictive coding principles to understand and treat auditory phantom perceptions.

Awards

Dr. Tziridis has demonstrated excellence in scientific research through multiple academic achievements. His contributions to auditory neuroscience, particularly in the study of tinnitus mechanisms, have been recognized within professional societies. His involvement in high-impact publications and collaborations has established his reputation in the field. As an active member of the German Neuroscience Society and the German Society for Otorhinolaryngology, his work continues to shape advancements in auditory sciences.

Selected Publications

Here are seven of his notable publications:

1. Tziridis, K., Rasheed, J., Kwiatkowska, M., Wright, M., Schlingensiepen, R. (2025). A single dose of AC102 reverts tinnitus by restoring ribbon synapses in noise-exposed Mongolian gerbils. MDPI International Journal of Molecular Science. Cited by numerous studies exploring neurotrophic treatment for tinnitus.
2. Tziridis, K., Maul, A., Rasheed, J., Krauss, P., Schilling, A., Schulze, H. (2024). Tinnitus is associated with increased extracellular matrix density in the auditory cortex of Mongolian gerbils. BMC Neuroscience. Referenced in discussions on extracellular matrix alterations in tinnitus pathology.
3. Schulze, H., Schilling, A., Krauss, P., Tziridis, K. (2023). The Erlangen Model of Tinnitus Development – New perspective and treatment strategy. HNO. Influential in shaping the understanding of tinnitus progression and intervention methods.
4. Schilling, A., Sedley, W., Gerum, R., Metzner, C., Tziridis, K., Maier, A., Schulze, H., Zeng, F.G., Friston K.J., Krauss P. (2023). Predictive coding and stochastic resonance as fundamental principles of auditory phantom perception. Brain. Cited in research discussing predictive models of tinnitus perception.
5. Tziridis, K., Friedrich, J., Brüggemann, P., Mazurek, B., Schulze, H. (2022). Estimation of Tinnitus-Related Socioeconomic Costs in Germany. MDPI International Journal of Environmental Research and Public Health. Frequently referenced in economic evaluations of hearing disorders.
6. Tziridis, K., Brunner, S., Schilling, A., Krauss, P., Schulze, H. (2022). Spectrally matched near-threshold noise for subjective tinnitus loudness attenuation based on stochastic resonance. Frontiers in Neuroscience. Significant in auditory neuromodulation research.
7. Tziridis, K., Forster, J., Wendler, O., Buchhaid-Dörfler, I., Krauss, P., Schilling, A., Sterna, E., Schulze, H. (2021). Tinnitus development is associated with synaptopathy of inner hair cells in Mongolian gerbils. European Journal of Neuroscience. Frequently cited in auditory synaptopathy studies.

Conclusion

Dr. Konstantin Tziridis has made remarkable contributions to auditory neuroscience, particularly in understanding and treating tinnitus. His work bridges basic neurobiology with translational research, offering new perspectives on auditory phantom perception and therapeutic strategies. His dedication to teaching, mentorship, and interdisciplinary collaboration continues to shape advancements in the field. Through his influential publications and leadership in scientific research, Dr. Tziridis remains a key figure in otolaryngology, fostering innovative approaches to hearing disorders.